Published November, 2009
By Robert Grutzmann and Christian Pilarsky
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This is a fundamental yet comprehensive guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research. It examines the world of cancer gene profiling in light of new advances.

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Published October, 2009
By Blake C. Meyers and Pamela J. Green
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

MicroRNAs constitute a particularly important class of small RNAs given their abundance, broad phylogenetic conservation and strong regulatory effects, with plant miRNAs uniquely divulging their ancient evolutionary origins and their strong post-transcriptional regulatory effects.

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Published October, 2009
By Anton A. Komar
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection.

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Published October, 2009
By Ray H. Gavin
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

In the ten years since the publication of the first edition, great advances in fluorescent labeling, optics, and sample preparation have significantly improved the imaging capability of microscopy, allowing for a continual refinement of our understanding of the cytoskeleton as a dynamic synergy of components.

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Published September, 2009
By Jeffrey A. Stuart
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

The volume is divided into three sections, which cover the transduction of information from mtDNA to functionally active respiratory complexes, mitochondrial reactive oxygen species (ROS) production as well as mtDNA damage and its repair, and the identification and quantification of heteroplasmic mtDNA mutations.

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Published September, 2009
By Keith DiPetrillo
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies.

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Published September, 2009
By Duncan J. Clarke
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Due to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly from a biochemical perspective, yet the expansion of research at the molecular and cellular levels continues to show a great deal of promise.

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Published September, 2009
By Hisashi Koga and H. Koga
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Now a major approach in the identification of certain gene product functions, reverse chemical genetics allows the identification of target genes to precede phenotypic changes created by specific small molecules.

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Published September, 2009
By Edgar Jacoby
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating: 1.00
Availability: Available

Chemogenomics aims toward the systematic identification of small molecules that interact with the products of the genome and modulate their biological function.

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Published August, 2009
By Preston B. Rich and Christelle Douillet
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

This second edition details the newest and most innovative techniques in this rapidly expanding field. It provides methods and assays that can be adapted and used in most specialties of biomedical and biotechnological fields.

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