Published August, 2007
By Tiziana Borsello
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms.

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Published August, 2007
By Mark T. Quinn, Frank R. DeLeo and Gary M. Bokoch
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This book provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders.

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Published June, 2007
By Maher Albitar
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins.

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Published June, 2007
By Paul J. Fairchild
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Immunological Tolerance: Methods and Protocols is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo.

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Published April, 2007
By Trygve O. Tollefsbol
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions.

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Published March, 2007
By Jun Zhang and Gregg Rokosh
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This book presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function.

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Published February, 2007
By Mouldy Sioud
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

These volumes review the most current methods for drug target discovery and validation. They explore how recent improvement in understanding the molecular mechanisms of human pathology is impacting drug target discovery in the laboratory and in real therapeutics, specifically for cancers and autoimmune disorders.

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Published February, 2007
By Fernando Vivanco
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Topics explored in this comprehensive volume include obtaining specific heart proteins, techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels.

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Published October, 2006
By Mouldy Sioud and Sioud Mouldy
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Target discovery is a field that has existed for several years but is so vibrant today because of the recent progress in our understanding of the molecular mechanisms of many human diseases and the technical advances in target identification and validation.

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Published September, 2006
By Inka Brockhausen
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

Another challenge for future research is to understand the glycodynamics of a cell, that is, how the cell responds to stimuli leading to biological and pathological changes in terms of alterations in glycosylation, and how this affects the biology of the cell.

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