Main description:

Often considered the prototypic autoimmune disease, Lupus is characterized by protean manifestations and affects a wide range of organ systems. Despite widespread availability of anti nuclear antibody testing and other technological diagnostic advances, the diagnosis of lupus can be elusive, difficult, and inexact. Treatment of the disease can also be challenging. Advances in immunology and biotechnology have led to a burgeoning world of new therapies in development that offer patients the real possibility of new therapies and physicians and scientists novel insights into the pathogenesis of this complicated immunological disease. Lupus Erythematosus: Clinical Evaluation and Treatment summarizes the clinical aspects of lupus facing the general clinician in the 21st century. In this invaluable, practical book, the reader will find introductory chapters regarding general diagnostic and treatment principles, followed by chapters addressing the lupus-specific organ manifestations. Special topics regarding pregnancy and comorbidities are also presented. Written by highly experienced physicians with special expertise in lupus, Lupus Erythematosus: Clinical Evaluation and Treatment is an indispensable reference for the common and not so common problems affecting patients with lupus.

Contents:

Introduction

EM Massarotti and PH Schur

1. SLE Epidemiology: Epidemiology Subtypes and Risk Factors for Development

JF Simard, and KH Costenbader

2. The Immunopathogenesis and Immunopathology of SLE

D Pisetsky

3. Diagnosis and Monitoring SLE

PH Schur

4. Clinical Monitoring of the Patient with Lupus

VP Bykerk

5. The Treatment of SLE: General Principles

EM Massarotti and PH Schur

6. Cutaneous Manifestations of Lupus Erythematosus

H Townsend, and RA Vleugels

7. Musculoskeletal Manifestations of SLE

S Helfgott

8. The Cerebrovascular System in SLE

R Sands

9. Pulmonary Manifestations of SLE

HJ Goldberg, and PF Dellaripa

10. Hematologic Manifestations of SLE

N Berliner

11. Renal Manifestations of SLE

M Dooley

12. Gastrointestinal Manifestations of SLE

RS Kalman and J Wolf

13. Neuropsychiatric Aspects of SLE

S Khoshbin

14. SLE and Pregnancy

B Bermas

15. Anti-phospholipid Antibody Syndrome

B Bermas

16. Lupus-Like Syndromes related to Drugs

J Merola

17. New and Emerging Therapies for SLE

EM Massarotti

18. Comorbidities in SLE

M Gayed, C-S Yee, S Bernatsky, C Gordon