Main description:

Medical microbiology concerns the nature, distribution and activities of microbes and how they impact on health and wellbeing, most particularly as agents of infection. Infections remain a major global cause of mortality and in most hospitals around one in ten of those admitted will suffer from an infection acquired during their stay. The evolution of microbes presents a massive challenge to modern medicine and public health. The constant changes in viruses such as influenza, HIV, tuberculosis, malaria and SARS demand vigilance and insight into the underlying process.

Building on the huge success of previous editions, Medical Microbiology 18/e will inform and inspire a new generation of readers. Now fully revised and updated, initial sections cover the basic biology of microbes, infection and immunity and are followed by a systematic review of infective agents, their associated diseases and their control. A final integrating section addresses the essential principles of diagnosis, treatment and management. An unrivalled collection of international contributors continues to ensure the relevance of the book worldwide and complementary access to the complete online version on Student Consult further enhances the learning experience.

Medical Microbiology is explicitly geared to clinical practice and is an ideal textbook for medical and biomedical students and specialist trainees. It will also prove invaluable to medical laboratory scientists and all other busy professionals who require a clear, current and most trusted guide to this fascinating field.

Contents:

Contents

PART 1

MICROBIAL BIOLOGY

1 Microbiology and medicine

2 Morphology and nature of micro-organisms

3 Classi?cation, identi?cation and typing of micro-organisms

4 Bacterial growth, physiology and death

5 Antimicrobial agents

6 Bacterial genetics

7 Virus-cell interactions

PART 2

INFECTION AND IMMUNITY

8 Immunological principles: antigens and antigen recognition

9 Innate and acquired immunity

10 Immunity in viral infections

11 Parasitic infections: pathogenesis and immunity

12 Immunity in bacterial infections

13 Bacterial pathogenicity

14 The natural history of infection

PART 3

BACTERIAL PATHOGENS AND ASSOCIATED DISEASES

15 Staphylococcus

16 Streptococcus and enterococcus

17 Coryneform bacteria, listeria and erysipelothrix

18 Mycobacterium

19 Environmental mycobacteria

20 Actinomyces, nocardia and tropheryma

J. M. Grange

21 Bacillus

22 Clostridium

T. V. Riley

23 Neisseria and moraxella

24 Salmonella

25 Shigella Bacillary dysentery

26 Escherichia

H. Chart

27 Klebsiella, enterobacter, proteus and other enterobacteria

28 Pseudomonads and non-fermenters

J. R. W. Govan

29 Campylobacter and helicobacter

J. M. Ketley

30 Vibrio, mobiluncus, gardnerella and spirillum

H. Chart

31 Haemophilus

32 Bordetella

N. W. Preston and R. C. Matthews

33 Legionella Legionnaires' disease; Pontiac fever

34 Brucella, bartonella and streptobacillus M. J. Corbel

35 Yersinia, pasteurella and francisella

M. J. Corbel

36 Non-sporing anaerobes

R. P. Allaker

37 Treponema and borrelia

A. Cockayne

38 LeptospiraLeptospirosis; Weil's disease

39 Chlamydia Genital and ocular infections; infertility; atypical pneumonia

40 Rickettsia, orientia, ehrlichia, anaplasma and coxiella

D. H. Walker and Xue-Jie Yu

41 Mycoplasmas Atypical pneumonia; genital tract infection

PART 4

VIRAL PATHOGENS AND ASSOCIATED DISEASES

42 Adenoviruses Respiratory disease; conjunctivitis; gut infections

43 Herpesviruses

I. Johannessen and M. M. Ogilvie

44 Poxviruses

T. H. Pennington

45 Papillomaviruses and polyomaviruses

H. A. Cubie

46 Hepadnaviruses Hepatitis B infection; deltavirus infection

47 Parvoviruses B19 infection; erythema infectiosum

48 Picornaviruses

I. Johannessen and S. M. Burns

49 Orthomyxoviruses In?uenza

50 Paramyxoviruses Respiratory infections; mumps; measles; Hendra/Nipah disease

51 Arboviruses: alphaviruses, ?aviviruses and bunyaviruses

A. D. T. Barrett and S. C. Weaver

52 Togavirus and hepacivirus Rubella; hepatitis C and E viruses

53 Arenaviruses and ?loviruses

H. Feldman, D. Safronetzand D. Falzarano

54 Reoviruses Gastro-enteritis

55 Retroviruses Acquired immune de?ciency syndrome; lymphoma

56 Caliciviruses and astroviruses Diarrhoeal disease

57 Coronaviruses Upper respiratory tract disease

58 Rhabdoviruses Rabies

59 Transmissible spongiform encephalopathies (prion diseases)

J. W. Ironside

PART 5

FUNGAL PATHOGENS, PARASITIC INFECTIONS AND MEDICAL ENTOMOLOGY

60 Fungi Super?cial, subcutaneous and systemic mycoses

61 Protozoa Malaria; toxoplasmosis; cryptosporidiosis; amoebiasis; trypanosomiasis; leishmaniasis; giardiasis; trichomoniasis

62 Helminths Intestinal worm infections; ?lariasis; schistosomiasis; hydatid disease

63 Arthropods Arthropod-borne diseases; ectoparasitic infections; allergy

PART 6

DIAGNOSIS, TREATMENT AND CONTROL OF INFECTION

64 Infective syndromes

65 Diagnostic procedures

66 Strategy of antimicrobial chemotherapy

67 Epidemiology and control of community infections

68 Hospital infection

69 Immunization

INDEX