Main description:

Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format.

Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases.

Contents:

Section I. GENERAL CONCEPTS AND TOOLS

Section II. NEUROLOGIC DISEASES

NEUROMETABOLIC DISORDERS

Mitochondrial Disorders

Lysosomal Disorders

Metal Metabolism Disorders

Vitamin Disorders

Lipid Metabolism Disorders

Other Metabolic Disorders

DEGENERATIVE DISORDERS

MOVEMENT DISORDERS

NEURO-ONCOLOGY

NEUROCUTANEOUS DISORDERS

EPILEPSY

WHITE MATTER DISEASES

NEUROPATHIES AND NEURONOPATHIES

MUSCLE AND NEUROMUSCULAR JUNCTION DISORDERS

STROKE

Section III. PSYCHIATRIC DISEASE

Section IV. A NEUROLOGIC AND PSYCHIATRIC GENE MAP