Main description:

Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.

Contents:

Chapter 1. Introduction-cancer pathways.- Chapter 2. Important molecules that have been targeted in cancers (mutations, biomarkers and tumor suppressors).- Chapter 3. New emerging molecules that are current focus of cancer research and hold promise.-Chapter 4. Different areas of research that have contributed immensely toward understanding of cancer:

a In silico (includes data mining, NGS, modelling, MDS etc)

b. Biophysics/structural biology

c. Omics (genomics, proteomics etc.)

d. Immunotherapy

e. Molecular and Cellular biology

f. Gene therapy

g. Microarray

h. Cancer Imaging

i. Animal Models