Main description:

This book covers all aspects of Wilms' tumor, the second most typical solid tumor in children. Its potential for complete cure underscores correct management of this tumor. To achieve this goal, the book aims to provide all necessary details for practicing Pediatric surgeons, Oncologists, Pediatricians, Urologists, and Medical students. Topics ranging from epidemiology, etiology, pathology, clinical features, diagnostic methods, surgery, chemotherapy, radiotherapy to cutting-edge inventions are described in great detail.Detailed descriptions of surgical techniques and their nuances will greatly benefit surgeons and surgical residents. Importantly, all the chapters are written by authors who have first-hand experience with clinical management. Thus the text ensures the practical application of theoretical details.

Contents:

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1. The History of Renal Tumors in Children

2. Epidemiology

3. Genetics and Molecular Biology

4. Tumor Microenvironment and Inflammatory Markers

5. Syndromic Wilms' Tumor

6. Familial Non-Syndromic Wilms' Tumor

7. Pathology

8. Clinical Presentation

9. Laboratory Workup

10. Imaging Studies

11. Diagnostic Biopsy

12. General Surgical Guidelines

13. Nephron-Sparing Surgery

14. Lymph Node Sampling

15. Minimally Invasive Surgery

16. Bench Surgery and Auto-Transplantation

17. Anesthetic concerns

18. Staging

19. Systemic Chemotherapy

20. Radiotherapy

21. Novel Tumor Directed Interventions

22. Wilms' tumor in resource challenged nations

23. Management of Resected Wilms' Tumor with Unknown Staging Status

24. Bilateral Wilms' Tumor

25. Wilms' Tumor in Horseshoe Kidney and Solitary Kidney

26. Very large tumors not responding to chemotherapy/locally infiltrating tumors

27. Intravascular extension and tumor thrombosis

28. Ureteral Extension

29. Ruptured tumors

30. Metastatic Wilms' tumor

31. Recurrent/ relapsed Wilms' tumor

32. Wilms' Tumor in Less than 6-month-old Infants

33. Wilms' tumor in adults

34. Nephrogenic rests and Nephroblastomatosis

35. Extrarenal Wilms' Tumor

36. Complications of treatment

37. Post-therapy surveillance of Wilms' tumor survivors

38. Prognosis and Outcomes

39. Non-Wilms' renal tumors